R3 has independently scored 9 probiotics for safety on a 0 to 10 scale. The average safety score is 2.2/10, 0 score 9.0 or higher, and Nature's Way Fortify Adults 50+ Extra Strength Probiotic, 50 Billion CFU leads the category at 3.5/10.
Across the 9 probiotics R3 scored, the median safety score is 1.7/10. The distribution below shows how many land in each safety band.
Highest safety score
Nature's Way Fortify Adults 50+ Extra Strength Probiotic, 50 Billion CFUSafety 3.5/10, the top of 9 probiotics R3 scored.
Lowest safety score
Florastor Daily Probiotic, Saccharomyces boulardii CNCM I-745, 250 mgSafety 1.0/10, the lowest in the set, scored the same way as every other product in the category.
R3 has independently scored 9 probiotics for safety, with an average safety score of 2.2/10 and a median of 1.7/10.
Nature's Way Fortify Adults 50+ Extra Strength Probiotic, 50 Billion CFU has the highest safety score among the 9 probiotics R3 scored. 0 of 9 score 9.0 or higher on safety. Sign in to see each product's exact safety score.
| 6 |
| Garden of Life Raw Probiotics Kids, 5 Billion CFU |
| 1.7 |
| 2.9 |
| 7 | Physician's Choice Probiotics 60 Billion CFU, 10 Strains + Organic Prebiotics | 1.7 | 3.0 |
| 8 | Align Probiotic 24/7 Digestive Support | 1.0 | 2.5 |
| 9 | Florastor Daily Probiotic, Saccharomyces boulardii CNCM I-745, 250 mg | 1.0 | 2.4 |
Source: R3 (2026). Safety scores on a 0 to 10 scale across 9 independently scored probiotics.