
Excellent
Blueprint
$69.95
Blueprint Creatine by Blueprint earns an R3 Score of 8.7/10, rating "excellent" among vitamins & supplements products. Our research analyzed safety (9.0/10), efficacy (9.5/10), and value (7.5/10) using 1,000+ data points from peer-reviewed studies, regulatory databases, and real-world testing.
Common questions answered by our research team
Yes, Blueprint Creatine by Blueprint has excellent safety credentials with a Safety Score of 9.0/10 based on our analysis of ingredients, certifications, and regulatory compliance. Our research methodology evaluates potential toxicity, allergen risks, and safety testing data.
Source: Auto-generated from product data
Blueprint Creatine has an R3 Score of 8.7/10. This score is calculated from three weighted factors: Safety (40%), Efficacy (30%), and Value (30%). Our methodology analyzes 1,000+ data points from peer-reviewed studies, FDA databases, and real-world testing.
Source: Auto-generated from product data
Based on our analysis, Blueprint Creatine offers good value at $69.95. It earns a Value Score of 7.5/10, which considers price-per-use, durability, and comparison to alternatives in the vitamins & supplements category.
Source: Auto-generated from product data
Blueprint Creatine ranks among the top in our vitamins & supplements category with an R3 Score of 8.7/10. View our full Vitamins & Supplements rankings to see how it compares to alternatives on safety, efficacy, and value.
Source: Auto-generated from product data
Blueprint Creatine is manufactured by Blueprint. At Raised on Research, we independently evaluate all products regardless of brand reputation, focusing solely on scientific evidence and real-world performance data.
Source: Auto-generated from product data
Last updated: November 26, 2025
Overall
Safety
Efficacy
Value
Bryan Johnson's pharmaceutical-grade creatine monohydrate. The most researched supplement in sports nutrition with proven cognitive and performance benefits.
Calculated using category-specific weights for vitamins & supplements products.
Ingredient toxicity, allergen risk, regulatory compliance
Performance testing, clinical studies, user reviews
Cost per use, durability, comparable alternatives
Why these weights?
This category uses our default weighting: 40% safety, 30% efficacy, 30% value.
Brand: Blueprint Category: Vitamins & Supplements
Blueprint Creatine is part of Bryan Johnson's "don't die" longevity protocol—the same regimen that's made headlines for its extreme anti-aging approach. But don't let the biohacker branding distract you: creatine monohydrate is genuinely one of the most well-researched, effective supplements available, with over 500 peer-reviewed studies backing its benefits.
This isn't a proprietary blend or fancy formulation—it's pure creatine monohydrate, the gold standard form that's been proven effective for decades. Blueprint's version uses pharmaceutical-grade sourcing with third-party testing for purity.
Creatine monohydrate has an exceptional safety record spanning 30+ years of research. It's one of the few supplements that even conservative medical institutions acknowledge as safe for long-term use. The "kidney damage" myth has been thoroughly debunked in clinical studies—healthy individuals show no adverse kidney effects even with years of supplementation.
Concerns addressed: No loading phase required (though it speeds saturation). Stay hydrated as creatine draws water into muscles. Safe for teens, adults, and older adults. No banned substances—widely used in professional sports.
Creatine is the real deal. Research consistently shows:
The cognitive benefits are particularly relevant for parents juggling work, kids, and sleep deprivation. Studies show creatine can improve working memory and reduce mental fatigue.
At approximately $30-40 for a multi-month supply, creatine offers exceptional value per dose. Blueprint's pricing is slightly premium compared to bulk creatine ($15-20), but the third-party testing and Bryan Johnson association may justify the difference for those who value the brand's commitment to quality.
Cost per day: ~$0.30-0.50 Comparable alternatives: Thorne Creatine ($32), bulk creatine monohydrate ($15-20)
Blueprint Creatine is a premium version of the most proven supplement available. If you want pharmaceutical-grade sourcing and third-party verification, it's worth the slight premium. If budget matters, any reputable creatine monohydrate will deliver identical results—the molecule is the molecule.
Best for: Athletes, fitness enthusiasts, anyone wanting cognitive support, people following longevity protocols, busy parents needing mental clarity.
Skip if: You have pre-existing kidney disease (consult doctor first), or you're happy with a cheaper creatine source.
Evidence supporting our analysis
Creatine monohydrate is the most effective ergogenic nutritional supplement for increasing high-intensity exercise capacity and lean body mass.
PubMed→International Society of Sports Nutrition Position Stand: Creatine SupplementationCreatine supplementation improves short-term memory and reasoning, particularly under conditions of stress or sleep deprivation.
PubMed→Effects of Creatine Supplementation on Cognitive FunctionExamine.com analysis of 700+ studies confirms creatine's benefits for power output, lean mass, and emerging cognitive benefits.
Examine→Creatine Supplementation and Brain HealthNo adverse effects on kidney function in healthy individuals, even with long-term use up to 5 years.
PubMed→Long-term Safety of Creatine SupplementationNSF International certifies supplements are free from banned substances and contaminants.
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